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Table of content 2009

Biology
Developing and validating an analytical method to control toxic metals in urine using ICP-MS
Validating the analysis method: Forensic assay of alcohol in whole blood
Assay of sitamaquine in Leishmania donovani strains by LC-MS/MS
Drug assays in biological samples using UPLC
Validation of Quantification Method for Drug X in Rat Plasma by LC-MS/MS
Separating and characterizating of products generated by Nocardia cyriacigeorgica
Characterizing microorganisms by two analysis methods: FT-IR spectroscopy and mass spectrometry MALDI-TOF
Developing the GC-MS method to quantify Testosterone : Epitestosterone ratio in female urine.

Environment
Adapting extraction and GC/MS analysis methods to esterified phenoxyacid families
The optimizing quantitative analysis in high pressure chromatography coupled with mass spectrometry
Developing and validating a analytical method to detect PCB
Optimizing and validating analysis method of sulfides in water by potentiometry
Chemical analysis of the Mediterranean gorgonians and structural characterization of bio-active metabolites
Quantifying the Levoglucosan in atmospheric aerosols by High Pressure Liquid Chromatography- Electrospray Ionization Ion Trap Mass Spectrometry
Dangerousness determination of old paints on metallic bridges in AES
Validating a new system that analyse the Selective Catalytic Reduction (SCR) of NOx (Nitrogen Oxides) by decane
Development method in GC of permanent gases separation

General
Qualification of thermostatic air oven
Quantifying of THM by HS-GC-MS in swimming pool water
Comparing retention in xanthine separation between a silica and titania stationary phase in HPLC
Liquid-Liquid Equilibria for Monoethylene Glycol + Water + xylene
Qualifying the Ultra-violet detector in a chromatography system
Optimization of a monolithic stationary phase for microchip electrochromatography

Materials
Experimental study on zirconium carbide ceramics expected to be used as coatings for fuel of fourth-generation nuclear reactors
Validating the analysis method for Cd, Cr and Pb in ceramics using ICP-AES
Optimizing the separation of nuclear fission products using an Isotachophoretic method
Revealing metamerism by spectrocolorimetry

Pharmaceutical
Research of Cyamemazine and its principal metabolites in urine using positive mode electrospray LC/MS
Comparison between SPE and MEPS - Application in fatty alcohol analysis.
Investigation of overloading of basic compounds in UHPLC - Influence of the mobile phase pH
Developing two High-Performance Liquid Chromatography methods to study the stability of a formulated growth factor
MANCO



Special Highlight


Drug assays in biological samples using UPLC
The pharmacology laboratory of Desgenettes Hospital performs assays bychromatographic methods in the fields of pharmacology (e.g. bio-equivalence)and toxicology for both the hospital and for forensic analysis. One of the analysis performed was the toxicological screening which allows drugs to be ide...

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Validating a new system that analyse the Selective Catalytic Reduction (SCR) of NOx (Nitrogen Oxides) by decane
Diesel engines emit toxic exhaust gas such as NOx (NO and NO2). These gases are not only dangerous to the environment, but also to our health. This is the reason why European standards impose a reduction of their emissions by 2014. In order to follow these norms, some research has to be done on the ...

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Optimization of a monolithic stationary phase for microchip electrochromatography
Analytical chemistry is an area in demand for methods allowing faster analysis and lower consumption of solvent. In this context “labs on a chip” were developed, which can combine all the analytical processes (sample preparation, separation, and detection) in a single device. Electrochromatograhy, ...

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Research of Cyamemazine and its principal metabolites in urine using positive mode electrospray LC/MS
The phenothiazine derivative cyamemazine is the most widely used antipsychotic neuroleptic drug in France. This medicine is used in order to treat Schizophrenia and lot of psychoses. The Pharmaco-Toxicology Laboratory of Edouard Herriot Hospital had noticed interference between this drug and the amp...

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