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Special Highlight
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Study of protein ligand interactions by Nuclear Magnetic Resonance
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Drug discovery is a particularly long process in the pharmaceutical field; therefore, different strategies aimaing to improve the development time and the success of this critical step have been employed. 2 of these strategies, extensive high throughput screenings (HTS), and combinatorial chemical s...
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Phenols derivatization method in GC-MS/MS
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Phenols belong to the pesticide family, which can be found in water, air and ground. Like every pesticide, they are environmentally threatening and very toxic for the human body. Analyses to detect phenol traces are carried out either on drinking water samples or residual waters. These kinds of pest...
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Amino acid analysis in royal jelly by HPLC
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The "Service Central d'Alayse (SCA) in a CNRS department. There were two principal activities at the food product laboratory: research and provision of services.
Royal jelly is the secretion of hypopharynged or brood food glands in the worker honey bee heads. Nowadays, there is a lot of foreig...
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Cyclosporin stability in Microtainer® EDTA tubes for its dosage over the time
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Cyclosporin (CsA), is a first line immunosuppressive agent with a narrow therapeutic range and a large inter-subject pharmacokinetic variability. Therapeutic drug monitoring of CsA, is used to improve patient care.
A previous in vitro (CsA free blood doped) study [1] showed CsA was absorbed int...
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