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Special Highlight
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Comparison of two methods to measure free thyroxin in blood serum
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The free thyroxin (FT4) is the main hormone secreted by the thyroid gland in the blood serum. The BIOMAG laboratory is a clinical laboratory. It uses an analytical method based on electro-chemiluminescence to measure it.
The Roche Diagnostics company has developed a new method to analyse FT4. ...
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Determination of three donors platelet grouping
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Each individual is charaterized by his/her own blood group. Various blood groups are grouped into systems, the main one being the ABO system, Rhesus and Kell systems.
Platelet grouping is mainly performed, for pregnant women, if there are anti-platelet antibodies in their system. Platelet group...
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Study of protein-protein interactions between UIM-SH3 domain of STAM2 and an AMSH peptide by NMR
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Cells internalization of proteins is regulated by membrane protein-protein interactions. Inside cells, the STAM2 protein encodes the transcription signal of endocytosis. Ubiquitin allows the recognition of targeted proteins to degrade, fixing on its surface. Ubiquitination is a reversible process: d...
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Development of an analytical method for the dosage of the methotrexate using LC-MS/MS
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In the 50’s, methotrexate (MTX) was discovered as an anticancer agent. It inhibits cellular enzymes and prevents cells replication. MTX is currently one of the most common drugs in cancerology, but it’s also the anchor drug in the treatment of rheumatoid arthritis (RA).
MTX is intracellularly...
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